Semax
In stockACTH (4-7)-Pro-Gly-ProHeptapeptide Met-Glu-His-Phe-Pro-Gly-Pro, an analogue of the ACTH(4-10) fragment with a Pro-Gly-Pro extension. Researchers study its copper binding, calcium signalling in brain slices and gene expression in rat brain regions.
Supplied as a single-chamber lyophilized vial with a colour-coded cap (Cognition & Focus).
Research literature, not dosing or treatment instructions.
- Semax was examined for copper(II) binding and for its effect on Cu(II)-catalysed reactive oxygen species production and amyloid-beta cytotoxicity. (PMID 40496623)
- Intracellular calcium dynamics were measured in rat hippocampal and cerebellar slices exposed to Semax. (PMID 41171324)
- Gene expression was analysed by RNA-Seq in rat brain regions after ACTH-like peptides including Semax. (PMID 40650034)
Add the solvent slowly along the vial wall; swirl gently, never shake. Allow to dissolve fully. Six-step guide with photos →
Concentration calculator only. Enter the mass being calculated; blend components are not added automatically. Products are for in-vitro research.
Refer to the product label and supplier documentation for storage conditions. Lot-specific storage and expiry information is not available here.
Each certificate is published with its lot number.
Questions about Semax
How much published research is there on Semax?
The research library's PubMed search for Semax returned 155 records on 5 October 2026, 9 of them reviews. The library lists 3 studies chosen for what they measured. ClinicalTrials.gov lists no registered study naming Semax (checked 5 October 2026).
Is Semax an approved medicine?
No medicinal product containing Semax is listed in Drugs@FDA (checked 5 October 2026), and the research material we supply is not a medicine. It is supplied for in-vitro laboratory research only, not for human or veterinary use.
What is Semax derived from?
Semax is an analogue of the ACTH(4-10) fragment with a Pro-Gly-Pro extension, with the sequence Met-Glu-His-Phe-Pro-Gly-Pro.
How does Semax differ from Selank?
Semax and Selank are both heptapeptides ending in Pro-Gly-Pro. Semax is an analogue of ACTH(4-10) and Selank an analogue of the tetrapeptide tuftsin.
How is the identity of Semax confirmed on a certificate?
A research-grade certificate of analysis typically reports identity by mass spectrometry and purity by HPLC. The mass result is read against the average molecular weight of 813.9 Da listed on this page. The research library's guide to reading a certificate explains each field.
Is this product for human use?
No. Peptency products are supplied for in-vitro research only. Not for human or veterinary use, not for diagnosis or therapy.
Where can I find shipping information?
Current shipping rates and delivery information are on the Shipping & payment page, and the rates that apply to your order are shown at checkout.
Often studied with
For research use only. Not for human or veterinary use.
What is Semax?
Semax is the heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro, an analogue of the ACTH(4-10) fragment with a Pro-Gly-Pro extension. Published work includes copper-binding chemistry, brain-slice calcium measurements and rat gene-expression studies. We supply Semax as a lyophilized vial for in-vitro laboratory research only.
What are the chemical identifiers of Semax?
Semax has the molecular formula C37H51N9O10S, an average molecular weight of 813.9 Da and CAS number 80714-61-0.
Chemistry checked against PubChem (CID 9811102), 5 October 2026; full chemistry record in the research library.
What does published research on Semax cover?
A PubMed search for Semax returned 155 records on 5 October 2026, 9 of them reviews. Our research library lists 3 of these studies, chosen for what they measured.
- Semax was examined for copper(II) binding and for its effect on Cu(II)-catalysed reactive oxygen species production and amyloid-beta cytotoxicity. (Tomasello et al., Bioinorg Chem Appl, 2025; PMID 40496623)
- Intracellular calcium dynamics were measured in rat hippocampal and cerebellar slices exposed to Semax. (Kolbaev et al., Bull Exp Biol Med, 2025; PMID 41171324)
- Gene expression was analysed by RNA-Seq in rat brain regions after ACTH-like peptides including Semax. (Filippenkov et al., Int J Mol Sci, 2025; PMID 40650034)
Mechanism, every cited study and the regulator records are on the Semax page of the research library. Papers are listed by what they measured, not as evidence of any use.
How is Semax supplied and stored?
Semax is supplied as a lyophilized (freeze-dried) powder in a sealed vial, for in-vitro laboratory research only. Our stated storage condition for the sealed lyophilized vial is 2 to 8 °C. The label and the lot certificate carry the lot-specific storage condition and expiry date.
What is the regulatory status of Semax?
Drugs@FDA lists no application naming semax as an active ingredient (checked 5 October 2026).
A regulator record is information about a database entry. It is not advice and not a statement that any use is lawful or unlawful in any country. How regulators approach research peptides.
Which related research pages and compounds are listed?
- Semax: chemistry, literature and regulatory status
- Semax compared with Selank
- How to read a certificate of analysis
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