Thymosin α1
In stockThymalfasin28-residue N-acetylated peptide first characterised from calf thymus in 1977, also known as thymalfasin. Researchers study its effects on dendritic cells and toll-like receptor signalling in cell culture.
Supplied as a single-chamber lyophilized vial with a colour-coded cap (Anti-Aging).
Research literature, not dosing or treatment instructions.
- Reviews describe effects on T cells, dendritic cells and cytokine production, and recombinant production methods. (PMID 20699109, PMID 17600290)
- Human monocyte-derived dendritic cells were exposed to toll-like receptor agonists in the presence of thymosin alpha 1. (PMID 26096650)
- Dendritic cells and the immune synapse were examined in a cell culture model of human cytomegalovirus infection. (PMID 38149577)
Add the solvent slowly along the vial wall; swirl gently, never shake. Allow to dissolve fully. Six-step guide with photos →
Concentration calculator only. Enter the mass being calculated; blend components are not added automatically. Products are for in-vitro research.
Refer to the product label and supplier documentation for storage conditions. Lot-specific storage and expiry information is not available here.
Each certificate is published with its lot number.
Questions about Thymosin α1
How much published research is there on Thymosin α1?
The research library's PubMed search for Thymosin α1 returned 954 records on 5 October 2026, 143 of them reviews. The library lists 4 studies chosen for what they measured. ClinicalTrials.gov lists 64 registered studies naming Thymosin α1 (checked 5 October 2026).
Is Thymosin α1 an approved medicine?
No centrally authorised medicine containing Thymosin α1 is listed in the EMA medicines database (checked 5 October 2026), and the research material we supply is not a medicine. It is supplied for in-vitro laboratory research only, not for human or veterinary use.
How is thymosin alpha 1 related to thymosin beta 4?
They are different peptides. Thymosin alpha 1 is a 28-residue N-acetylated peptide first characterised from calf thymus in 1977. Thymosin beta 4 (TB-500) is a 43-residue peptide that binds G-actin.
How is the identity of Thymosin α1 confirmed on a certificate?
A research-grade certificate of analysis typically reports identity by mass spectrometry and purity by HPLC. The mass result is read against the average molecular weight of 3108.3 Da listed on this page. The research library's guide to reading a certificate explains each field.
What other names is Thymosin α1 published under?
Thymosin α1 is also written Thymalfasin, Thymosin alpha-1 and Thymosin alpha 1. The catalog lists it under the name Thymosin α1.
Is this product for human use?
No. Peptency products are supplied for in-vitro research only. Not for human or veterinary use, not for diagnosis or therapy.
Where can I find shipping information?
Current shipping rates and delivery information are on the Shipping & payment page, and the rates that apply to your order are shown at checkout.
Often studied with
For research use only. Not for human or veterinary use.
What is Thymosin α1?
Thymosin alpha 1 is a 28-residue N-acetylated peptide first described and characterised from calf thymus in 1977. Cell-culture work examines its effects on dendritic cells and toll-like receptor signalling. We supply Thymosin α1 as a lyophilized vial for in-vitro laboratory research only.
What are the chemical identifiers of Thymosin α1?
Thymosin α1 has the molecular formula C129H215N33O55, an average molecular weight of 3108.3 Da and CAS number 62304-98-7.
Chemistry checked against PubChem (CID 16130571), 5 October 2026; full chemistry record in the research library.
What does published research on Thymosin α1 cover?
A PubMed search for Thymosin α1 returned 954 records on 5 October 2026, 143 of them reviews. Our research library lists 4 of these studies, chosen for what they measured.
- Reviews describe effects on T cells, dendritic cells and cytokine production, and recombinant production methods. (Li et al., Peptides, 2010; PMID 20699109; Garaci et al., Ann N Y Acad Sci, 2007; PMID 17600290)
- Human monocyte-derived dendritic cells were exposed to toll-like receptor agonists in the presence of thymosin alpha 1. (Giacomini et al., Expert Opin Biol Ther, 2015; PMID 26096650)
- Dendritic cells and the immune synapse were examined in a cell culture model of human cytomegalovirus infection. (Espinar-Buitrago et al., Int Immunopharmacol, 2023; PMID 38149577)
Mechanism, every cited study and the regulator records are on the Thymosin α1 page of the research library. Papers are listed by what they measured, not as evidence of any use.
How is Thymosin α1 supplied and stored?
Thymosin α1 is supplied as a lyophilized (freeze-dried) powder in a sealed vial, for in-vitro laboratory research only. Our stated storage condition for the sealed lyophilized vial is 2 to 8 °C. The label and the lot certificate carry the lot-specific storage condition and expiry date.
What is the regulatory status of Thymosin α1?
The EMA medicines database (checked 5 October 2026) lists no centrally authorised medicine naming Thymosin α1 (searched as thymalfasin or thymosin alpha) as an active substance. National authorisations are not in that dataset.
No SmPC, PIL or PAR document in MHRA Products matches the exact name (checked 5 October 2026).
A regulator record is information about a database entry. It is not advice and not a statement that any use is lawful or unlawful in any country. How regulators approach research peptides.
Which related research pages and compounds are listed?
- Thymosin α1: chemistry, literature and regulatory status
- Thymosin peptides
- How to read a certificate of analysis
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