GHK-Cu
In stockCopper tripeptide-1Copper(II) complex of the tripeptide Gly-His-Lys, first isolated from human plasma. Researchers study it in fibroblast and animal models of extracellular-matrix turnover, tissue remodeling and gene expression.
Supplied as a single-chamber lyophilized vial with a colour-coded cap (Recovery & Repair).
Research literature, not dosing or treatment instructions.
- GHK binds copper(II) with an affinity similar to the copper transport site on albumin, and the complex is called GHK-Cu. (PMID 18644225)
- The X-ray and solution structures of the copper(II) complexes of GHK have been determined, with spectroscopic data on their redox properties. (PMID 21780203)
- In cultured fibroblasts the GHK-Cu complex increased collagen synthesis over a range of concentrations, independent of any change in cell number. (PMID 3169264)
- Reviews describe effects on extracellular-matrix turnover, including glycosaminoglycan synthesis and metalloproteinase activity, and genome-wide expression datasets. (PMID 26236730)
Add the solvent slowly along the vial wall; swirl gently, never shake. Allow to dissolve fully. Six-step guide with photos →
Concentration calculator only. Enter the mass being calculated; blend components are not added automatically. Products are for in-vitro research.
Refer to the product label and supplier documentation for storage conditions. Lot-specific storage and expiry information is not available here.
Each certificate is published with its lot number.
Questions about GHK-Cu
How much published research is there on GHK-Cu?
The research library's PubMed search for GHK-Cu returned 165 records on 5 October 2026, 15 of them reviews. The library lists 6 studies chosen for what they measured. ClinicalTrials.gov lists 2 registered studies naming GHK-Cu, 1 of them sponsored by LifeWave, Inc. (checked 5 October 2026).
Is GHK-Cu an approved medicine?
No centrally authorised medicine containing GHK-Cu is listed in the EMA medicines database (checked 5 October 2026), and the research material we supply is not a medicine. It is supplied for in-vitro laboratory research only, not for human or veterinary use.
Why do published formula and weight values for GHK-Cu differ between sources?
PubChem records the copper(II) complex as a cation (C14H23CuN6O4+, 402.92 Da). Supplier materials may be described as the neutral complex or as a salt, so formula and weight can differ by a few mass units between sources. The lot certificate gives the form supplied.
How does GHK-Cu differ from AHK-Cu?
GHK-Cu and AHK-Cu are copper(II) complexes of two tripeptides that differ only at the first residue, glycine in GHK and alanine in AHK. GHK-Cu has a large literature; AHK-Cu has a small one.
How is the identity of GHK-Cu confirmed on a certificate?
A research-grade certificate of analysis typically reports identity by mass spectrometry and purity by HPLC. The mass result is read against the average molecular weight of 402.92 Da listed on this page. The research library's guide to reading a certificate explains each field.
What other names is GHK-Cu published under?
GHK-Cu is also written Copper tripeptide-1 and GHK Cu. The catalog lists it under the name GHK-Cu.
Is this product for human use?
No. Peptency products are supplied for in-vitro research only. Not for human or veterinary use, not for diagnosis or therapy.
Where can I find shipping information?
Current shipping rates and delivery information are on the Shipping & payment page, and the rates that apply to your order are shown at checkout.
Often studied with
For research use only. Not for human or veterinary use.
What is GHK-Cu?
GHK-Cu is the copper(II) complex of glycyl-L-histidyl-L-lysine, a three-residue peptide first isolated from human plasma. The literature describes it in cell-culture and animal work on extracellular-matrix turnover, tissue remodeling and gene expression. We supply GHK-Cu as a lyophilized vial for in-vitro laboratory research only.
What are the chemical identifiers of GHK-Cu?
GHK-Cu has the molecular formula C14H23CuN6O4+, an average molecular weight of 402.92 Da and CAS number 89030-95-5.
PubChem records the copper(II) complex as a cation (C14H23CuN6O4+). Supplier materials may be described as the neutral complex or as a salt, so formula and weight can differ by a few mass units between sources.
Chemistry checked against PubChem (CID 71587328), 5 October 2026; full chemistry record in the research library.
What does published research on GHK-Cu cover?
A PubMed search for GHK-Cu returned 165 records on 5 October 2026, 15 of them reviews. Our research library lists 6 of these studies, chosen for what they measured.
- GHK binds copper(II) with an affinity similar to the copper transport site on albumin, and the complex is called GHK-Cu. (Pickart, J Biomater Sci Polym Ed, 2008; PMID 18644225)
- The X-ray and solution structures of the copper(II) complexes of GHK have been determined, with spectroscopic data on their redox properties. (Hureau et al., Chemistry, 2011; PMID 21780203)
- In cultured fibroblasts the GHK-Cu complex increased collagen synthesis over a range of concentrations, independent of any change in cell number. (Maquart et al., FEBS Lett, 1988; PMID 3169264)
- Reviews describe effects on extracellular-matrix turnover, including glycosaminoglycan synthesis and metalloproteinase activity, and genome-wide expression datasets. (Pickart et al., Biomed Res Int, 2015; PMID 26236730)
Mechanism, every cited study and the regulator records are on the GHK-Cu page of the research library. Papers are listed by what they measured, not as evidence of any use.
How is GHK-Cu supplied and stored?
GHK-Cu is supplied as a lyophilized (freeze-dried) powder in a sealed vial, for in-vitro laboratory research only. Our stated storage condition for the sealed lyophilized vial is 2 to 8 °C. The label and the lot certificate carry the lot-specific storage condition and expiry date.
What is the regulatory status of GHK-Cu?
The EMA medicines database (checked 5 October 2026) lists no centrally authorised medicine naming GHK-Cu (searched as prezatide or copper tripeptide) as an active substance. National authorisations are not in that dataset.
No SmPC, PIL or PAR document in MHRA Products matches the exact name (checked 5 October 2026).
A regulator record is information about a database entry. It is not advice and not a statement that any use is lawful or unlawful in any country. How regulators approach research peptides.
Which related research pages and compounds are listed?
- GHK-Cu: chemistry, literature and regulatory status
- GHK-Cu compared with AHK-Cu
- Copper-binding tripeptides
- How to read a certificate of analysis
Related compounds in the catalog: